Dipeptide Peptidase 4 (DPP-4) Inhibitors Market - Growth, Trends, and Forecast (2019 - 2024)

Market Overview

The global DPP-4 inhibitors market was valued at USD 10.5 billion in 2018 and is expected to record a CAGR of 4% during 2019-2024. The North American DPP-4 drugs segment of the market studied accounted for the highest revenue, in 2018, and Latin America is expected to register the highest CAGR, of approximately 6%, during the forecast period.

Increasing diabetes type-2 and obesity populations will drive the growth of the market in the forecast period.

Increase in clinical trials on the DPP-4 drugs will also boost the market growth in the forecast period.

Scope of the Report

The DPP-4 inhibitors market is segmented by brands and covers the following brands: Januvia, Onglyza/Kombiglyze, Tradjenta, Nesina, Galvus, and other brands. The report is segmented into five regions: North America, Asia-Pacific, Middle East & Africa, Latin America, and Europe.

Key Market Trends 

The Tradjenta Market will Surpass Merck’s Januvia During the Forecast Period

The global Tradjenta market is expected to register a CAGR of 5.7 %, during the forecast period, 2019-2024, and is expected to surpass the Januvia market, which held the maximum market share in 2018. The Tradjenta market includes its combination Jentadueto and Jentadueto XR, a combination of linagliptin (Tradjenta) and metformin hydrochloride, for use in the treatment of type 2 diabetes. The type-2 diabetes drug, Tradjenta (linagliptin) was not launched in Germany, because of a decision by the county’s reimbursement authority, which concluded that it doesn’t provide any additional benefits, compared to the medicines already on the market.

North America Holds the Highest Market Share

The Asia-Pacific holds 32% of the market share in the global DPP-4 market, followed by North America, which holds the highest market share. Increasing diabetes prevalence in established and emerging countries is expected to drive the market. This increase, over the years, is due to the overall effect of individual-level factors, like an increasing median age of the population and health factors, including obesity and inactivity levels among people.

Lowering birth rates, along with increasing life expectancy in countries like Japan, Italy, Germany, and France, which have a high percentage of the geriatric population, are expected to drive the growth of the market.

Competitive Landscape

Merck held the highest market share in the DPP-4 market in 2018 and is expected to maintain its position until 2022. After that, it may witness a decline in market share, due to the expected launch of a generic version of Sitagliptin in 2022.

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1 INTRODUCTION

1.1 Study Deliverables

1.2 Study Assumptions

1.3 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

4.1 Market Overview

4.2 Drivers

4.3 Restraints

4.4 Porter’s Five Forces Analysis

4.4.1 Bargaining Power of Suppliers

4.4.2 Bargaining Power of Consumers

4.4.3 Threat of New Entrants

4.4.4 Threat of Substitute Products and Services

4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION

5.1 By Drug

5.1.1 Dipeptidyl Peptidase – 4 (DPP-4) Inhibitors (Value and Volume 2012-2024)

5.1.1.1 Januvia (Sitagliptin)

5.1.1.2 Onglyza (Saxagliptin)

5.1.1.3 Tradjenta (Linagliptin)

5.1.1.4 Vipidia/Nesina (Alogliptin)

5.1.1.5 Galvus (Vildagliptin)

5.2 Geography

5.2.1 North America

5.2.1.1 United States (Value and Volume, 2012-2024)

5.2.1.1.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.1.1.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.1.2 Canada (Value and Volume, 2012-2024)

5.2.1.2.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.1.2.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.1.3 Rest of North America (Value and Volume, 2012-2024)

5.2.1.3.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.1.3.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2 Europe

5.2.2.1 France (Value and Volume, 2012-2024)

5.2.2.1.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.1.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.2 Germany (Value and Volume, 2012-2024)

5.2.2.2.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.2.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.3 Italy (Value and Volume, 2012-2024)

5.2.2.3.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.3.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.4 Spain (Value and Volume, 2012-2024)

5.2.2.4.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.4.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.5 United Kingdom (Value and Volume, 2012-2024)

5.2.2.5.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.5.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.6 Russia (Value and Volume, 2012-2024)

5.2.2.6.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.6.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.2.7 Rest of Europe (Value and Volume, 2012-2024)

5.2.2.7.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.2.7.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.3 Latin America

5.2.3.1 Mexico (Value and Volume, 2012-2024)

5.2.3.1.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.3.1.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.3.2 Brazil (Value and Volume, 2012-2024)

5.2.3.2.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.3.2.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.3.3 Rest of Latin America (Value and Volume, 2012-2024)

5.2.3.3.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.3.3.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4 Asia-Pacific

5.2.4.1 Japan (Value and Volume, 2012-2024)

5.2.4.1.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.1.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.2 South Korea (Value and Volume, 2012-2024)

5.2.4.2.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.2.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.3 China (Value and Volume, 2012-2024)

5.2.4.3.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.3.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.4 India (Value and Volume, 2012-2024)

5.2.4.4.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.4.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.5 Australia (Value and Volume, 2012-2024)

5.2.4.5.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.5.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.6 Vietnam (Value and Volume, 2012-2024)

5.2.4.6.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.6.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.7 Malaysia (Value and Volume, 2012-2024)

5.2.4.7.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.7.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.8 Indonesia (Value and Volume, 2012-2024)

5.2.4.8.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.8.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.9 Philippines (Value and Volume, 2012-2024)

5.2.4.9.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.9.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.10 Thailand (Value and Volume, 2012-2024)

5.2.4.10.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.10.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.4.11 Rest of Asia-Pacific (Value and Volume, 2012-2024)

5.2.4.11.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.4.11.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5 Middle East & Africa

5.2.5.1 Saudi Arabia (Value and Volume, 2012-2024)

5.2.5.1.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.1.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5.2 Iran (Value and Volume, 2012-2024)

5.2.5.2.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.2.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5.3 Egypt (Value and Volume, 2012-2024)

5.2.5.3.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.3.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5.4 Oman (Value and Volume, 2012-2024)

5.2.5.4.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.4.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5.5 South Africa (Value and Volume, 2012-2024)

5.2.5.5.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.5.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

5.2.5.6 Rest of Middle East & Africa (Value and Volume, 2012-2024)

5.2.5.6.1 By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

5.2.5.6.2 By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

6 MARKET INDICATORS

6.1 Type-1 Diabetes Population (2012-2024)

6.2 Type-2 Diabetes Population (2012-2024)

7 COMPETITIVE LANDSCAPE

7.1 Company Profiles

7.1.1 Merck And Co.

7.1.2 AstraZeneca

7.1.3 Bristol Myers Squibb

7.1.4 Novartis

7.1.5 Takeda Pharmaceuticals

7.1.6 Eli Lilly

7.1.7 Boehringer Ingelheim

7.2 Company Share Analysis

7.2.1 Merck And Co.

7.2.2 AstraZeneca

7.2.3 Takeda Pharmaceuticals

7.2.4 Novartis

7.2.5 Eli Lilly & Boehringer Ingelheim

8 MARKET OPPORTUNITIES AND FUTURE TRENDS

MARKET SEGMENTATION

By Drug

Dipeptidyl Peptidase – 4 (DPP-4) Inhibitors (Value and Volume 2012-2024)

Januvia (Sitagliptin)

Onglyza (Saxagliptin)

Tradjenta (Linagliptin)

Vipidia/Nesina (Alogliptin)

Galvus (Vildagliptin)

Geography

North America

United States (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Canada (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Rest of North America (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Europe

France (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Germany (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Italy (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Spain (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

United Kingdom (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Russia (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Rest of Europe (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Latin America

Mexico (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Brazil (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Rest of Latin America (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Asia-Pacific

Japan (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

South Korea (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

China (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

India (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Australia (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Vietnam (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Malaysia (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Indonesia (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Philippines (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Thailand (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Rest of Asia-Pacific (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Middle East & Africa

Saudi Arabia (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Iran (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Egypt (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Oman (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

South Africa (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)

Rest of Middle East & Africa (Value and Volume, 2012-2024)

By Drug (Januvia, Onglyza, Tradjenta, Vipidia, Galvus)

By Company (Merck, AstraZeneca, Novartis, Eli Lilly & Boehringer Ingelheim, Takeda Pharmaceutical)